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The rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, and transcriptional regulation. This allows researchers to more quickly define the role of their gene in various biological contexts to progress the understanding of human disease.
Low oxygen tension (hypoxia) and ensuing metabolic reprograming are recurrent themes in cancer. Solid tumors have significant hypoxic regions that harbor aggressive tumor cells. How do tumors sense and adapt to oxygen? How is metabolism rewired to sustain tumor growth under oxygen stress?
Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of alterations to DNA sequence. These changes can be cell or tissue-specific, and can be passed on to multiple generations. Next-generation sequencing (NGS) offers unprecedented ...
Researchers have been touting the virtues of 3D cell culture over traditional 2D culture for years. But what are the differences between cells grown in 2D and 3D, and how do these differences impact your experiments?
Queremos agradecer a todos los Asistentes al XXXVIX Congreso de la SEBBM, y en especial a los más de 250 investigadores que se pasaron por nuestro Stand, por el interés mostrado en todas las novedades, y ofertas que habíamos preparado para el Congreso, y en especial por habernos acompañado y ser parte de los...
Researchers have been touting the virtues of 3D cell culture over traditional 2D culture for years. But what are the differences between cells grown in 2D and 3D, and how do these differences impact your experiments?
La técnica de CRISPR-Cas9 ha supuesto una revolución muy importante en los últimos años, cambiando la forma de entender la función génica.
