Estándar de referencia Tru-Q 1 (5_ Tier)(formato gDNA) 50ng_µl, 1µg

Next generation sequencing (NGS) platforms give researchers much greater power when profiling tumor samples. However, the use of NGS presents challenges surrounding sample variability, platform bias, and potential failure to detect biomarkers. Horizon’s standards are appropriate for any NGS library preparation including whole-genome, whole-exome, custom capture and targeted amplicon panels. Horizon has developed this Quality-Seq (Q-Seq) NGS Reference Standard range to support the development and continued validation of Next Generation Sequencing platforms. The Tru-Q DNA Reference Standard portfolio covers multiple endogenous SNPs, insertions and deletions. Tru-Q NGS DNA Reference Standard 1 (5% Tier) covers 10 mutations at 5% allelic frequency in genomic DNA format. These may be diluted to even lower allelic frequencies using our Tru-Q 0 Wild Type standard. Furthermore, because the Tru-Q series has 4 different standards at the 5% alleleic frequency range, you may use rotate these as “blinded” samples for proficiency testing in your laboratory.

These standards are available only in gDNA format.

Technical Data

• Genes Covered BRAF, EGFR, FLT3, IDH1, JAK2, KRAS, MEK, NOTCH1, NRAS, PIK3CA Cosmics 1,500+
• Allelic Frequencies 5% for verified variants
• Buffer Tris-EDTA (10mM Tris-HCl, 1mM EDTA), pH 8.1
• Product information- please check in the Horizon webpage https://www.horizondiscovery.com