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Información de Contacto

Cultek, S.L.U.  MADRID
Av. Cardenal Herrera Oria, 63
28034 Madrid (Spain) 
Tel. Centralita: +34 917 290 333
Tel. At. Cliente:  +34 902 04 4000 
Fax:   34 91 358 17 61
E-mail: info@cultek.com
Cultek, S.L.U. BARCELONA
Tel. Centralita:+34 938 611 660
Tel. At. Cliente:+34 902 04 4000
Fax:+34 93 860 03 53
E-mail: cultekbarna@cultek.com

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PERKINELMER HORIZON
Horizon

La empresa

Dharmacon Research, Inc. fue fundada en 1995, y su principal producto era la síntesis de RNA mediante una nueva tecnología, llamada 2-ACE RNA. Más tarde, esta tecnología se convirtió en un estándar global para la síntesis de RNA. 

A finales de los años 90, Dharmacon se especializó en una nueva e incipiente tecnología científica, el llamado silenciamiento génico. Lo hizo con su primer producto, el siGenome, que es un pequeño RNA de interferencia.

Dharmacon, es líder mundial en el suministro de oligonucleótidos RNA de alta calidad, de small interfering RNAs (siRNAs) y de una amplia gama de productos y tecnologías relacionados con interferencia de RNA (RNAi), de importante aplicación e introducción en investigación biotecnológica y farmacéutica.

Dharmacon pertenece al Horizon Discovery Group

PRODUCTOS

Catálogos y flyers

Videos

Welcome to Horizon Discovery, a PerkinElmer company

A complete overview of the Horizon Discovery product offerings including RNA synthesis and RNAi technologies via Dharmacon and continued innovation in CRISPR gene editing, cell line engineering, functional genomic screening, cell panel screening, and cell line derived reference standards. Additionally Horizon licenses a CHOSOURCE™ CHO-K1 GS knockout bioprocessing cell line and PinPoint™ base editing technology for therapeutic development.

A 2-minute intro to gene function studies

Learn more about Dharmacon solutions for gene function studies including RNAi, ORFs, and CRISPR technologies.

What happens to the protein in a knockout cell line?

An overview of the possible fates of a protein after CRISPR knockout. This video covers how to validate your knockout cell line by combining techniques like western blotting and functional assays.

What is CRISPR interference or CRISPRi?

CRISPR interference (CRISPRi) a novel method for specific gene knockdown at the transcriptional level enabling scientists to better understand the biological pathways, processes and pathologies of disease. The Horizon CRISPRi system uses a deactivated Cas9 nuclease (dCas9) fused to our proprietary SALL1-SDS3 repressor construct to block transcription of target genes in combination with the first available synthetic single guide RNAs for CRISPRi.

Choosing a Dharmacon siRNA product line and format

Sometimes having too many choices is more difficult than having too few. We are here to help. This brief video will walk through some simple questions to guide you in the process of choosing which of the four Dharmacon siRNA product lines will best suit your needs. You’ll need to think about the types of cells you will use, the types of genes you want to knock down, and how important premium specificity is to your experiments.

CRISPR-Cas9 format selection guide

Overwhelmed by the choices for gene editing reagents? Horizon Discovery walks you through all the options and helps you find what will be best for your CRISPR experiment.