Control negativo para edición génica CRISPR sgRNA Edit-R en formto lentiviral

Edit-R CRISPRa Lentiviral sgRNA Non-targeting controls are recommended as negative controls for experiments using CRISPRa lentiviral sgRNAs in human and mouse cells. The Edit-R CRISPRa Lentiviral sgRNA Non-targeting controls are designed to have a minimum of three mismatches or gaps to all potential PAM-adjacent targets in human, mouse and rat genomes. When using these controls, changes in cellular viability or gene expression likely reflect nonspecific cellular responses that can be used as a baseline for comparison to cells treated with target-specific reagents.